BACE : lead target for orchestrated therapy of Alzheimer's disease
Alzheimer's disease Amyloid beta-protein precursor Aspartic proteinases Alzheimer Disease Amyloid Precursor Protein Secretases sähkökirjat
John Wiley & Sons
2010
EISBN 9780470594070
BACE : APP processing, and signal transduction in Alzheimer's disease / Dale E. Bredesen and Edward H. Koo.
Identification of BACE as a target in Alzheimer's disease / Robert L. Heinrikson and Sukanto Sinha.
BACE biological assays / Alfredo G. Tomasselli and Michael J. Bienkowski.
Peptidic, peptidomimetic, and HTS based BACE inhibitors / James P. Beck and Dustin J. Mergott.
Fragment-based approaches for identification of BACE inhibitors / Andreas Kuglstatter and Michael Hennig.
Structure-based drug design of BACE inhibitors : technical and practical aspects of preparation, 3-dimensional structure, and computational analysis / Felix F. Vajdos, Veerabahu Shanmugasundaram, and Alfredo G. Tomasselli.
Pharmacological models for preclinical testing : from mouse to dog to non-human primates / Jason L. Eriksen, Michael Paul Murphy, and Elizabeth Head.
Adsorption, distribution, metabolism, excretion (ADME), efficacy, and toxicology for BACE inhibitors / Ishrut Hussain and Emmanuel Demont.
Clinical trials for disease-modifying drugs such as BACE inhibitors / Henry H. Hsu.
Future strategies for development of novel BACE inhibitors : anti-APP B-site antibody and APP binding small molecule approaches for Alzheimer's disease / Beka Solomon ... [et al.].
Identification of BACE as a target in Alzheimer's disease / Robert L. Heinrikson and Sukanto Sinha.
BACE biological assays / Alfredo G. Tomasselli and Michael J. Bienkowski.
Peptidic, peptidomimetic, and HTS based BACE inhibitors / James P. Beck and Dustin J. Mergott.
Fragment-based approaches for identification of BACE inhibitors / Andreas Kuglstatter and Michael Hennig.
Structure-based drug design of BACE inhibitors : technical and practical aspects of preparation, 3-dimensional structure, and computational analysis / Felix F. Vajdos, Veerabahu Shanmugasundaram, and Alfredo G. Tomasselli.
Pharmacological models for preclinical testing : from mouse to dog to non-human primates / Jason L. Eriksen, Michael Paul Murphy, and Elizabeth Head.
Adsorption, distribution, metabolism, excretion (ADME), efficacy, and toxicology for BACE inhibitors / Ishrut Hussain and Emmanuel Demont.
Clinical trials for disease-modifying drugs such as BACE inhibitors / Henry H. Hsu.
Future strategies for development of novel BACE inhibitors : anti-APP B-site antibody and APP binding small molecule approaches for Alzheimer's disease / Beka Solomon ... [et al.].
