Acetaminophen : properties, clinical uses and adverse effects

Acetaminophen sähkökirjat
Gazelle [distributor]
2012
EISBN 9781619423756
""ACETAMINOPHEN ""; ""ACETAMINOPHEN ""; ""CONTENTS ""; ""PREFACE ""; ""ACETAMINOPHEN (PARACETAMOL): PROPERTIES, CLINICAL USES, AND ADVERSE EFFECTS""; ""ABSTRACT ""; ""1. INTRODUCTION ""; ""2. PROPERTIES ""; ""2.1. Chemistry ""; ""2.2. Pharmacokinetics ""; ""2.2.1. Absorption ""; ""2.2.1.1. Immediate Release ""; ""2.2.1.2. Extended Release ""; ""2.2.1.3. Intravenous ""; ""2.2.2. Distribution ""; ""2.2.2.1. Spinal Fluid""; ""2.2.2.2. Placental Barrier ""; ""2.2.2.3. Breast Milk ""; ""2.2.3. Metabolism ""; ""2.2.4. Elimination ""; ""2.2.5. Fetus, Neonates, Infants, and Children""
""2.2.6. Geriatric """"3. CLINICAL USES ""; ""3.1. Antipyresis ""; ""3.2. Analgesia ""; ""4. SPECIAL POPULATIONS ""; ""4.1. Chronic Liver Disease ""; ""4.2. Renal Disease ""; ""4.3. Calorie Restricted Patients ""; ""4.4. HIV ""; ""4.5. Gilbert�s Syndrome ""; ""5. ADVERSE EVENTS ""; ""5.1. Allergy and Hypersensitivity ""; ""5.2. Central Nervous System ""; ""5.3. Gastrointestinal ""; ""5.4. Hemotologic and Hemostatic ""; ""5.5. Hepatic Toxicity ""; ""5.6. Pregnancy and Lactation ""; ""5.7. Renal ""; ""6. DDIS ""; ""6.1. Overdose ""; ""6.1.1. NAC Treatment ""
""3. long term acetaminophen ingestion can improve skeletal muscle structure and function""""4. acetaminophen possesses cardioprotective and neuroprotective properties ""; ""5. acetaminophen exhibits potent antioxidant activity ""; ""conclusions and perspectives ""; ""conflict of interest statement ""; ""acknowledgments ""; ""references ""; ""advanced methods for the removal of acetaminophen from water ""; ""abstract ""; ""1. introduction ""; ""2. pharmaceuticals as emergent pollutants ""; ""3. acetaminophen in water resources ""; ""4. acetaminophen removal and degradation ""
""5.a. Reduction of Body Temperature Due to APAP in Humans """"5.b. Reduction of Body Temperature in Experimental Animal Models of Liver Injury""; ""6. RELEVANCE OF BODY TEMPERATURE FOR APAP-INDUCED ALF ""; ""6.1. Effects of Hypothermia on the Development of Brain Edema and Intracranial Hypertension in ALF""; ""6.2. Effects of Hypothermia on the Progression of Liver Injury""; ""CONCLUSIONS ""; ""REFERENCES ""; ""NOVEL APPLICATIONS OF ACETAMINOPHEN ""; ""ABSTRACT ""; ""1.INTRODUCTION ""; ""2. CHRONIC ACETAMINOPHEN INGESTION CAN IMPROVE BLOOD GLUCOSE CONTROL ""
""7. ACETAMINOPHEN FORMULATIONS """"7.1. Combinations ""; ""7.2. IV Formulation ""; ""CONCLUSION ""; ""REFERENCES ""; ""CLINICAL AND EXPERIMENTAL RELEVANCE OF HYPOTHERMIA IN ACETAMINOPHEN HEPATOTOXICITY ""; ""ABSTRACT ""; ""1. INTRODUCTION ""; ""2. APAP-INDUCED HEPATOTOXICITY IN PATIENTS WITH ALF""; ""3. APAP-INDUCED HEPATOTOXICITY IN EXPERIMENTAL MODELS""; ""3.a. Determinants of APAP-Induced Hepatotoxicity in Experimental Animal Models ""; ""3.b. Histopathology ""; ""4. MECHANISMS OF APAP-INDUCED LIVER INJURY ""; ""5. BODY TEMPERATURE, APAP AND THE LIVER ""
""2.2.6. Geriatric """"3. CLINICAL USES ""; ""3.1. Antipyresis ""; ""3.2. Analgesia ""; ""4. SPECIAL POPULATIONS ""; ""4.1. Chronic Liver Disease ""; ""4.2. Renal Disease ""; ""4.3. Calorie Restricted Patients ""; ""4.4. HIV ""; ""4.5. Gilbert�s Syndrome ""; ""5. ADVERSE EVENTS ""; ""5.1. Allergy and Hypersensitivity ""; ""5.2. Central Nervous System ""; ""5.3. Gastrointestinal ""; ""5.4. Hemotologic and Hemostatic ""; ""5.5. Hepatic Toxicity ""; ""5.6. Pregnancy and Lactation ""; ""5.7. Renal ""; ""6. DDIS ""; ""6.1. Overdose ""; ""6.1.1. NAC Treatment ""
""3. long term acetaminophen ingestion can improve skeletal muscle structure and function""""4. acetaminophen possesses cardioprotective and neuroprotective properties ""; ""5. acetaminophen exhibits potent antioxidant activity ""; ""conclusions and perspectives ""; ""conflict of interest statement ""; ""acknowledgments ""; ""references ""; ""advanced methods for the removal of acetaminophen from water ""; ""abstract ""; ""1. introduction ""; ""2. pharmaceuticals as emergent pollutants ""; ""3. acetaminophen in water resources ""; ""4. acetaminophen removal and degradation ""
""5.a. Reduction of Body Temperature Due to APAP in Humans """"5.b. Reduction of Body Temperature in Experimental Animal Models of Liver Injury""; ""6. RELEVANCE OF BODY TEMPERATURE FOR APAP-INDUCED ALF ""; ""6.1. Effects of Hypothermia on the Development of Brain Edema and Intracranial Hypertension in ALF""; ""6.2. Effects of Hypothermia on the Progression of Liver Injury""; ""CONCLUSIONS ""; ""REFERENCES ""; ""NOVEL APPLICATIONS OF ACETAMINOPHEN ""; ""ABSTRACT ""; ""1.INTRODUCTION ""; ""2. CHRONIC ACETAMINOPHEN INGESTION CAN IMPROVE BLOOD GLUCOSE CONTROL ""
""7. ACETAMINOPHEN FORMULATIONS """"7.1. Combinations ""; ""7.2. IV Formulation ""; ""CONCLUSION ""; ""REFERENCES ""; ""CLINICAL AND EXPERIMENTAL RELEVANCE OF HYPOTHERMIA IN ACETAMINOPHEN HEPATOTOXICITY ""; ""ABSTRACT ""; ""1. INTRODUCTION ""; ""2. APAP-INDUCED HEPATOTOXICITY IN PATIENTS WITH ALF""; ""3. APAP-INDUCED HEPATOTOXICITY IN EXPERIMENTAL MODELS""; ""3.a. Determinants of APAP-Induced Hepatotoxicity in Experimental Animal Models ""; ""3.b. Histopathology ""; ""4. MECHANISMS OF APAP-INDUCED LIVER INJURY ""; ""5. BODY TEMPERATURE, APAP AND THE LIVER ""
